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Administered through subcutaneous injections, AOD 9604 is typically dosed at 500mcg/day

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LIST OF ABBREVIATIONS ASD Autism Spectrum Disorders mtDNA Mitochondrial DNA ATP Adenosine Triphosphate PD Parkinson’s Disease ETC Electron Transport Chain ROS Reactive Oxygen Species CESLAC Short and Long Acyl-carnitines GDF15 Growth Differentiation Factor 15 FGF21 Fibroblast Growth Factor 21 LTA Ligand Lipoteichoic Acid LPS Lipopolysaccharide RNS Reactive Nitrogen Species GSH Reduced Glutathione GSSG Oxidized Glutathione SAM S-adenosylmethionine SAH S-adenosyl-homocysteine rRNA Ribosomal RNA tRNAs Transfer RNAs nDNA Nuclear DNA SNPs Single Nucleotide Polymorphisms AGC1 Aspartate/Glutamate Carrier MELAS Mitochondrial Encephalomyopathy, Lactic Acidosis, And Stroke-like Events GWAS Genomic-wide Association Study CHARGE Childhood Autism Risk from Genes and Environment AMD Atkins Modified Diet SSADH Succinic Semialdehyde Dehydrogenase EEG Electroencephalogram MECP2 Methyl-CpG-binding Protein 2 mGluR5 Metabotropic Glutamate Receptor 5 nc-RNA Non-coding RNA ASO Antisense Oligonucleotides saRNAs Small Activating RNAs circRNA Circular RNAs ecDNA Extrachromosomal DNA ZFN Zinc-finger Nucleases CONSENT FOR PUBLICATION Not applicable